Perlstein Lab

Leave no mutation behind

Perlstein Lab PBC is a San Francisco-based biotech startup and public benefit corporation focused on precision orphan drug discovery.

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  • 1 in 12 people has an orphan disease. 95% of orphan diseases have no treatment.

  • Each disease is caused
    by a spectrum of genetic mutations.

  • Perlstein Lab studies each mutation
    in model organisms to produce precision medicine.


RNAseq and MOA

As the cell biology lead at Perlstein Lab, I spend a lot of time thinking about ways to better understand the mechanism of action of the hits from our primary screens. There are many experiments one can do to try to narrow down what pathway their compound is affecting such as cell biology experiments in […]

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